| 发明名称 |
SUBSTITUTED PYRAZINE DERIVATIVES |
| 摘要 |
The present invention provides substituted pyrazine derivatives of Formula (I), that are CRF1 receptor antagonists, including human CRF1 receptors. Thi s invention also relates to use of compounds of the invention for treating a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders, particularly anxiety- related disorders and mood disorders.
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| 申请公布号 |
CA2480497(A1) |
申请公布日期 |
2003.11.06 |
| 申请号 |
CA20032480497 |
申请日期 |
2003.04.17 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY LLC |
发明人 |
HOFFMAN, ROBERT L.;FU, JIAN-MIN;VERHOEST, PATRICK R.;CORBETT, JEFFREY W.;ENNIS, MICHAEL D.;FRANK, KRISTINE E. |
| 分类号 |
G01N33/50;A61K31/4965;A61K31/497;A61P1/00;A61P1/14;A61P3/04;A61P3/08;A61P5/00;A61P7/12;A61P9/00;A61P11/06;A61P15/08;A61P17/00;A61P17/06;A61P17/14;A61P21/00;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P29/00;A61P31/18;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D241/20;C07D403/12;C12Q1/02;G01N33/15;(IPC1-7):C07D241/20;A61K31/499 |
主分类号 |
G01N33/50 |
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