发明名称 |
Labeled oligonucleotides, methods for making same, and compounds useful therefor |
摘要 |
Selectively functionalized oligonucleotides, methods for making same, and compounds useful therefor are disclosed. The oligonucleotides can be selectively functionalized with a first conjugate group at the 3'-terminial position and optionally functionalized with a second conjugate group at the 5'-terminal position and/or one or more internucleotides. Alternatively, the oligonucleotides can be selectively functionalized with a first conjugate group at the 5'-terminal position and optionally functionalized with a second conjugate group at one or more internucleotides. In yet another embodiment, the oligonucleotides can be functionalized with a first conjugate group at one or more internucleotides and with a second conjugate group at one or more different internucleotides.
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申请公布号 |
US2003208061(A1) |
申请公布日期 |
2003.11.06 |
申请号 |
US20010823031 |
申请日期 |
2001.03.30 |
申请人 |
MANOHARAN MUTHIAH;GUZAEV ANDREI P. |
发明人 |
MANOHARAN MUTHIAH;GUZAEV ANDREI P. |
分类号 |
C07H21/00;(IPC1-7):C07H21/04;C12P19/34 |
主分类号 |
C07H21/00 |
代理机构 |
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