ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA

摘要

A method for enhancing learning and memory or treating amnesia. The method includes administrating to a subject in need thereof a compound of the formula (I) : each of Ar>1<, AR>2<, AND AR>3<, independently, is phenyl, thienyl, furyl, or pyrrolyl ; each of R>1<, R>2<, R>3<, R>4<, R>5<, AND R>6<, independently, is H, nitro, halogen, R, OH, OR, C(O)OH, C(O)OR, C(O)SH, C(O)SR, C(O)NH>2<, C(O)NHR, C(O)NRR', ROH, ,ROR', RSH, RSR', ROC(O)R'OH, NHR, NRR', RNHR', or RNR'R'', or R>1< AND R>2< TOGETHER, R>3< AND R>4< TOGETHER, OR R>5< AND R>6< together are ORO ; wherein each of R, R', and R'', independently is C>1< SIMILAR C>6< alkyl ; and n is 1, 2, or 3. The compound is in an effective amount for enhancing learning and memory or treating amnesia.