摘要 |
The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of ArnB amino transferases, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of ArnB, and compounds and compositions that affect ArnB activity. |
申请人 |
STRUCTURAL GENOMIX, INC.;NEWMAN, JANET;BADGER, JOHN;HENDLE, JORG;NOLAND, BRIAN;BUCHANAN, SEAN, GRANT |
发明人 |
NEWMAN, JANET;BADGER, JOHN;HENDLE, JORG;NOLAND, BRIAN;BUCHANAN, SEAN, GRANT |