Recombinant nucleic acid molecules are described. The molecules have a first nucleic acid sequence encoding an antigen containing two or more cytolytic T lymphocyte (CTL) epitopes and analogues thereof which can be recognised by a CD8+ T cell. Peptides encoded by the molecules and vectors and compositions containing these molecules are also described. Methods of eliciting an immune response using these molecules are also described.
申请公布号
WO02094313(A3)
申请公布日期
2003.11.06
申请号
WO2002GB02336
申请日期
2002.05.20
申请人
POWDERJECT VACCINES, INC.;POWDERJECT RESEARCH LIMITED