| 摘要 |
<p>Two-dimensional and/or three-dimensional polymeric or extended solid arrays, such as arrays of a polydiacetylene backbone, are used to evaluate the organic/water partition coefficient and/or oral absorptivity and/or transcellular permeability of a compound by monitoring the change in the fluorescence or phosphorescence of the array upon exposure to the compound and comparing it to a known change in fluorescence or phosphorescence, respectively. The method can also be used to evaluate the ability of a compound to bind to a protein.</p> |
