发明名称 |
TISSUE GROWTH METHOD AND APPARATUS |
摘要 |
A method for growing tissue in vitro includes the steps of:(i) providing a deformable substrate which is seeded with tissue-forming cells and which defines at least one flow channel containing a fluid culture medium;(ii) applying, substantially parallel to the flow channel, a cyclically varying load to the substrate, which load deforms the substrate to provide mechanical cueing for the cells; and(iii) inhibiting the flow of culture medium in one direction of the flow channel so that the deformation of the substrate causes a net flow of the culture medium along the flow channel in the opposing direction, thereby refreshing the culture medium in the flow channel. |
申请公布号 |
WO0250242(A3) |
申请公布日期 |
2003.11.06 |
申请号 |
WO2001GB05657 |
申请日期 |
2001.12.19 |
申请人 |
UNIVERSITY COLLEGE LONDON;BROWN, ROBERT, ALBERT;BLUNN, GORDON |
发明人 |
BROWN, ROBERT, ALBERT;BLUNN, GORDON |
分类号 |
C12M3/00;C12N5/08 |
主分类号 |
C12M3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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