摘要 |
<p>Compounds of formula (I) or a pharmaceutically acceptable salt thereof <CHEM> wherein: V is selected from the group consisting of a covalent bond and CH2; W is selected from the group consisting of a covalent bond, CH2 and CH2CH2; X is selected from the group consisting of a covalent bond and CH2; Y is selected from the group consisting of a covalent bond, CH2 and CH2CH2; Z is selected from the group consisting of CH2 and CH2CH2, and CH2CH2CH2; L1 is selected from the group consisting of a covalent bond and (CH2)n; n is 1-5; R1 is selected from the group consisting of (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), and (l); R2 is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, aminoalkyl, aminocarbonylalkyl, benzyloxycarbonyl, cyanoalkyl, dihydro-3-pyridinylcarbonyl, hydroxy, hydroxyalkyl, phenoxycarbonyl, and -NH2; are useful for controlling synaptic transmission in mammal.</p> |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BUNNELLE, WILLIAM H.;BARLOCCO, CRISTINA DANIELA;DAANEN, JEROME F.;DART, MICHAEL J.;MEYER, MICHAEL D.;RYTHER, KEITH B.;SCHRIMPF, MICHAEL R.;SIPPY, KEVIN B.;TOUPENCE, RICHARD B. |