发明名称 NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE
摘要 <p>The invention relates to new products of formula (I): in which: Y represents oxygen or sulphur, Z represents C=CH2, CH-CH3 or CH2, R1 represents hydrogen, morpholinyl or the radical. In which the two nitrogen atoms are linear or form a cyclic radical, X represents carbonyl, alkylene or alkenylene, linear or branched, containing at most 6 carbon atoms optionally interrupted by oxygen or sulphur, R4, R5 and R6 represent hydrogen, a protective group of the nitrogen, alkyl, cycloalkyl, aryl and arylalkyl optionally substituted, R2 represents alkyl optionally substituted by aryl, heteroaryl or -NR4R5, R3 represents alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl optionally substituted, these products being in all isomer forms and the salts, as medicaments.</p>
申请公布号 EP1358171(A2) 申请公布日期 2003.11.05
申请号 EP20020700386 申请日期 2002.01.23
申请人 AVENTIS PHARMA S.A. 发明人 DEPREZ, PIERRE;PATEK, MARCEL
分类号 C07D243/08;A61K31/17;A61K31/175;A61K31/36;A61K31/495;A61K31/496;A61K31/551;A61P1/00;A61P3/14;A61P5/18;A61P9/00;A61P9/12;A61P19/00;A61P19/02;A61P19/08;A61P25/08;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07C273/18;C07C275/24;C07C275/26;C07C275/28;C07C275/34;C07C275/42;C07D295/12;C07D295/13;C07D295/18;C07D317/58;C07D333/20;C07D407/12;(IPC1-7):C07D295/12;C07C275/30;C07D295/20 主分类号 C07D243/08
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