发明名称 N-(3,3-Dimethylindolin-6-yl){2-[(4-pyridylmethyl)amino}(3-pyridyl)}carboxamide and pharmaceutical compositions thereof.
摘要 Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 EP1358184(A1) 申请公布日期 2003.11.05
申请号 EP20020717325 申请日期 2002.01.11
申请人 AMGEN INC. 发明人 CHEN, GUOQING;ADAMS, JEFFREY;BEMIS, JEAN;BOOKER, SHON;CAI, GUOLIN;CROGHAN, MICHAEL;DIPIETRO, LUCIAN;DOMINGUEZ, CELIA;ELBAUM, DANIEL;GERMAIN, JULIE;GEUNS-MEYER, STEPHANIE;HANDLEY, MICHAEL;HUANG, QI;KIM, JOSEPH, L.;KIM, TAE-SEONG;KISELYOV, ALEXANDER;OUYANG, XIAOHU;PATEL, VINOD, F.;SMITH, LEON, M.;STEC, MARKIAN
分类号 C07D401/14;A61K31/4436;A61K31/444;A61K31/4709;A61K31/496;A61K31/501;A61K31/506;A61K31/5377;A61P9/10;A61P11/06;A61P15/08;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D213/82;C07D401/12;C07D405/12;C07D405/14;C07D407/14;C07D409/04;C07D409/12;C07D409/14;C07D413/14;C07D417/14;C07D471/04;(IPC1-7):C07D409/12 主分类号 C07D401/14
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