发明名称 THIAZOLE DERIVATIVES
摘要 Compounds of formula I <IMG> as well as pharmaceutically usable salts and esters thereof, wherein R1, R2 and R3 have the significance given in claim 1, inhibit the binding of adhesive proteins to t he surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical preparations in the control or preventon of neoplasms, tumour metastasing, osteoporosis, Paget's disease, diabetic retin opathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, kidney failure as well as infections caused by viruses, bacteria or fungi.</ SDOAB>
申请公布号 CA2257322(C) 申请公布日期 2003.11.04
申请号 CA19982257322 申请日期 1998.12.30
申请人 F. HOFFMANN-LA ROCHE AG 发明人 HILPERT, KURT;EDENHOFER, ALBRECHT;ALIG, LEO;WELLER, THOMAS
分类号 C07D277/20;A61K31/00;A61K31/425;A61K31/426;A61K31/427;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/4545;A61K31/535;A61K31/5375;A61K31/5377;A61P9/00;A61P13/00;A61P13/12;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P27/00;A61P27/02;A61P31/00;A61P31/04;A61P31/12;A61P35/00;A61P35/04;A61P43/00;C07D207/04;C07D277/24;C07D277/48;C07D277/56;C07D295/04;C07D417/02;C07D417/06;(IPC1-7):C07D277/56;C07D417/14;A61K31/47;A61K31/495;A61K31/54 主分类号 C07D277/20
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