发明名称 Nitric oxide donors and pharmaceutical compositions containing them
摘要 The present invention provides a compound containing at least one sulfhydryl group and at least one NO donor group, wherein said compound contains one or more protected sulfhydryl groups linked to at least one aromatic ring or a heteroaromatic ring with a nitrogen in the ring structure, which ring is substituted by one or more substitutes bearing at least one terminal -ONO2 group. The present invention further provides pharmaceutical compositions comprising one or more of said compounds as an active ingredient.
申请公布号 US6642260(B2) 申请公布日期 2003.11.04
申请号 US20020041680 申请日期 2002.01.09
申请人 YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM 发明人 HAJ-YEHIA ABDULLAH
分类号 A61K31/21;A61K31/222;A61K31/385;A61K31/426;A61K31/4365;A61K31/44;A61P9/08;A61P9/10;C07C321/10;C07C321/28;C07C323/12;C07C323/19;C07C323/20;C07C323/56;C07C323/62;C07C327/32;C07D213/70;C07D213/79;C07D213/80;C07D213/82;C07D277/14;C07D277/20;C07D277/56;C07D339/04;C07D339/08;C07D495/04;(IPC1-7):A61K31/44;C07D213/62 主分类号 A61K31/21
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