发明名称 |
Crustacean antimicrobial peptides |
摘要 |
The invention concerns antimicrobial peptides obtained from penaeid prawns having the following characteristics: a molecular mass of about 5 to 7 kDa; a pHi not less than 9; an N-terminal portion comprising a region (A) of about 15 to 25 amino acids rich in proline; and a C-terminal portion comprising a region (B) of about 20 to 30 amino acids and containing 6 cysteine residues forming three intramolecular disulfide bonds. The invention also concerns the nucleic acid sequences coding for said peptides and enabling their production by genetic engineering.
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申请公布号 |
US6642203(B1) |
申请公布日期 |
2003.11.04 |
申请号 |
US20000463125 |
申请日期 |
2000.04.12 |
申请人 |
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
DESTOUMIEUX DELPHINE;BACHERE EVELYNE;BULET PHILIPPE |
分类号 |
A61K38/00;A61P31/00;C07K14/435;C12N15/12;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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