| 发明名称 |
3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors |
| 摘要 |
The present invention relates to certain 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives that inhibit kinases, in particular VEGFR and/or PDGFR kinases. Pharmaceutical compositions comprising these compounds, methods of treating diseases mediated by kinases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing them are also disclosed.
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| 申请公布号 |
US6642232(B2) |
申请公布日期 |
2003.11.04 |
| 申请号 |
US20020268082 |
申请日期 |
2002.10.10 |
| 申请人 |
SUGEN, INC. |
发明人 |
MATTSON MATTHEW;VOJKOVSKY TOMAS;LIANG CONGXIN;TANG PENG CHO;GUAN HUIPING |
| 分类号 |
A61K31/404;A61K31/454;A61K31/4545;A61K31/5377;A61P3/10;A61P9/10;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P43/00;C07D401/14;C07D403/06;C07D403/12;C07D403/14;C07D413/14;(IPC1-7):A61K31/537 |
主分类号 |
A61K31/404 |
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