摘要 |
The present invention refers to chemical compounds of formula (I); <CHEM> wherein X<1>, X<2>, X<3> and X<4>, n, R<1>, R<2> and R<3> and pharmaceutically acceptable salts and prodrugs thereof, and the use thereof in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity. |