发明名称 Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
摘要 A polyester containing one or more free COOH groups and having a carboxyl to hydroxyl ratio greater than one, wherein the polyester contains a member selected from the group consisting of L-lactic acid, D-lactic acid, DL-lactic acid, malic acid, citric acid, å-caprolactone, ñ-dioxanone, å-caproic acid, alkylene oxalate, cycloalkylene oxalate, alkylene succinate, â-hydroxybutyrate, substituted or unsubstituted trimethylene carbonate, 1,5-dioxepan-2-one, 1,4-dioxepan-2-one, glycolide, glycolic acid, L-lactide, D- lactide, DL-lactide, meso-lactide, and any optically active isomers, racemates or copolymers thereof. Provided that citric acid, å-caprolactone and glycolide are members of the polyester.
申请公布号 NZ513072(A) 申请公布日期 2003.10.31
申请号 NZ20000513072 申请日期 2000.01.26
申请人 POLY-MED, INC 发明人 SHALABY, SHALABY W;JACKSON, STEVEN A;MOREAU, JACQUES-PIERRE
分类号 A61K38/00;A61K9/52;A61K38/04;A61K38/22;A61K38/27;A61K47/48;A61P35/00;A61P43/00;C07K7/23;C07K14/47;C07K14/59;C07K14/655;C07K19/00;C08G63/00;C08G63/06;C08G63/08;C08G63/64;C08G63/91;C08G81/00;C08J5/00;C08J7/04;C08L67/00;C08L101/16;(IPC1-7):C08G63/08 主分类号 A61K38/00
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