Applicator for delivering a liquid or semi-solid topical formulation into a mucosal cavity, for example, a vagina

摘要

Described is a unique vaginal/ano-rectal applicator for the uniform delivery of any topical formulations to treat and/or prevent any infection and/or abnormal conditions of mucosa cavity caused by any pathogen and/or disease. The applicator is illustrated in FIG. 13. A plurality of slots regularly spaced from each other are provided in the external wall. In this specific version, the expulsion element and the reservoir are also one single element. The expulsion element is a piston-like structure (10) that comprises the formulation provided in a pouch (11). In this embodiment, the connector element (5) is telescopically insertable in the piston-like structure (10). The pouch is made of a material of low resistance to compression. To break this membrane, a tapered element is provided at the proximal end of the internal wall. FIG. 13 shows this tapered element (9) as a disc provided with a pointed portion. The disc sits on the proximal end of the internal wall, the pointed portion facing the pouch (11). In use, the piston-like structure (10) is pressed by the user, the membrane is thus pierced by the pointed portion, and the formulation is thus forced through the diffusion channel, and expelled through the perforations. FIG. 13a is a perspective view illustrating an applicator. FIG. 13b is a side elevational view illustrating the dimensions in inches of the applicator of FIG. 13a in both insertion position and actuated position. FIG. 13c is an exploded view of the applicator of FIG. 13a.