发明名称 |
CHROMATOGRAPHIC PROCESS FOR OBTAINING HIGHLY PURIFIED CYCLOSPORIN A AND RELATED CYCLOSPORINS |
摘要 |
The present invention relates to a novel chromatographic process which is suitable for the purification of cyclosporin-containing crude extracts on industrial scale. In this process, the conventional preparative chromatographic separation methods are completely or at least partially replaced by the simulated moving bed method (SMB). The cyclosporin A obtained corresponds both to the quality requirements of USP XXIII and of EUROPEAN PHARMACOPOEIA, 2nd Edition 1995. |
申请公布号 |
IL125807(A) |
申请公布日期 |
2003.10.31 |
申请号 |
IL19970125807 |
申请日期 |
1997.03.14 |
申请人 |
ARZNEIMITTELWERK DRESDEN GMBH |
发明人 |
|
分类号 |
B01D15/02;A61K38/00;B01D15/34;C07K1/16;C07K1/20;C07K7/64;(IPC1-7):B01D15/02 |
主分类号 |
B01D15/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|