发明名称 Bicyclic oxazolidinone compounds, pharmaceuticals thereof and their use as antibacterial agents
摘要 Described is a compound of formula I, where: W is O or S; X is -S(=O)m-, or -NR3-; Y is -O-, -NH-, -CH2-, or -S(=O)m-; R1 is optionally substituted C1-4alkyl; R2 is H, C1-6alkyl that is optionally substituted with 1-3 halo, cyclopropyl, -OC1-4alkyl, -NH2, -NHC1-6alkyl, or -N(C1- 6alkyl)2; n is 0 or 1 with the proviso that where n is 0, Y is -CH2-. Also described is a pharmaceutical composition comprising the compound of formula I as defined above. The compound of formula I is useful for treating microbial infections.
申请公布号 NZ515754(A) 申请公布日期 2003.10.31
申请号 NZ20000515754 申请日期 2000.05.17
申请人 PHARMACIA & UPJOHN COMPANY 发明人 GENIN, MICHAEL J;BARBACHYN, MICHAEL R;HESTER, JACKSONB;JOHNSON, PAUL D
分类号 A61K31/422;A61K31/4709;A61K31/538;A61P17/00;A61P27/02;A61P31/04;C07D413/04;(IPC1-7):IPC7:C07;IPC7:;C07D41;C07D413/10;C07D4;C07D410;A61K31/404;A61K31/470;A61K31/537;A61K31/498;A61K31/541;A61P31/00 主分类号 A61K31/422
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