PROCESS FOR PREPARING N,N,6-TRIMETHYL-2-(4-METHYLPHENYL)- IMIDAZO-(1,2-A)-PYRIDINE-3-ACETAMIDE AND SALTS THEREOF

摘要

The process comprises reducing the hydroxyester of formula (X) by making it react in DMF successively with an imine salt of formula (XIII) formed "in situ" with thionyl chloride and dimethylformamide, and subsequent reduction with an appropriate reducer in order to form the ester of formula (XII) which is then reacted with dimethylamine in a polyhydroxylated solvent medium in appropriate temperature conditions.