发明名称 |
PEPTIDE DEFORMYLASE ACTIVATED PRODRUGS |
摘要 |
This invention provides a method for inhibiting the growth of a microorganism that expresses Peptide Deformylase by contacting the microorganism with an effective amount of the compound described herein. This method inhibits the growth of gram-positive and gram-negative microorganism, e.g., S. aureus, S. epidermidis, K. pneumoniae, E. aerogenes, and E. cloacae. This method can be practiced in vitro, ex vivo and in vivo. Further provided is a method for alleviating the symptoms of an infection by a Peptide Deformylase expressing microorganism in a subject by administering or delivering to the subject an effective amount of the compound described above. |
申请公布号 |
WO03088913(A2) |
申请公布日期 |
2003.10.30 |
申请号 |
WO2003US11981 |
申请日期 |
2003.04.17 |
申请人 |
NEWBIOTICS, INC.;SERGEEVA, MARIA, V.;DOPPALAPUDI, VENKATA, RAMANA |
发明人 |
SERGEEVA, MARIA, V.;DOPPALAPUDI, VENKATA, RAMANA |
分类号 |
A61K47/48;A61K49/00;C12Q1/18 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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