COMPOSITIONS AND METHODS FOR THE ACCELERATION OF PROTEIN SECRETION DYNAMICS
摘要
The present invention provides compositions and methods for modulating the secretion of transcriptionally regulated proteins from recombinant cells. More particularly, the present invention provides compositions and methods for accelerating the secretion dynamics of human insulin from recombinant cells using nonsense mediated mRNA decay of preproinsulin mRNA transcript.
申请公布号
WO03088916(A2)
申请公布日期
2003.10.30
申请号
WO2003US12228
申请日期
2003.04.21
申请人
GEORGIA TECH RESEARCH CORPORATION;TANG, SHIU-CHENG;SAMBANIS, ATHANASSIOS