| 摘要 |
The invention concerns a method and device for comparing the sequence of test DNA molecule contained in a first solution with the sequence of a reference comprising the steps of extracting (11) single-stranded DNA molecules from the first solution; mixing (14) a part of the solution containing the test DNA molecules with reference DNA molecules (13) attached to a solid support and having a sequence complementary to that of the sequence of reference; filtering (15) the mixture with a filter having a cut-off size chosen not to retain eventual free test DNA molecules but to retain the solid support and the test DNA molecules attached to it; introducing a solvent (16) in the filtered solution; illuminating (17) the final mixture; and measuring (18) the opacity or turbidity of the illuminated mixture, a non transparency indicating a non identity of the test and reference DNA sequences.
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