发明名称 |
Method for separating unmodified hemoglobin from cross-linked hemoglobin |
摘要 |
A method for separating unmodified hemoglobin from cross-linked hemoglobin in a hemoglobin solution. The method involves contacting the hemoglobin solution with a least one dissociating agent to form a dissociation solution wherein unmodified tetrameric hemoglobin is dissociated to form hemoglobin dimers. The hemoglobin dimers are then separated from the dissociation solution, while retaining the cross-linked hemoglobin in the dissociation solution.
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申请公布号 |
US2003203350(A1) |
申请公布日期 |
2003.10.30 |
申请号 |
US20030420630 |
申请日期 |
2003.04.18 |
申请人 |
BIOPURE CORPORATION |
发明人 |
LIGHT WILLIAM R.;GAWRYL MARIA S.;LACCETTI ANTHONY J.;HOUTCHENS ROBERT A. |
分类号 |
C07K1/14;C07K14/805;(IPC1-7):A01N1/02 |
主分类号 |
C07K1/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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