| 摘要 |
A new soft tissue implant filling material is disclosed. The surgically implantable soft tissue implant filling material has good aesthetic properties, as measured by viscosity and elasticity, and good elimination properties. One embodiment of such a new filling material is a gel which comprises three components. The first component is a water soluble polymer or hydrogel that has a high molecular weight. Alternatively, the first component is both crosslinked and has a high molecular weight. The second component of the filling material is a water-soluble polymer that has a molecular weight and a molecular weight distribution that is essentially under the renal threshold molecular weight of the polymer. The third component of this filling material is saline, which is used to dissolve the polymer and to adjust the osmolality of the polymer. In addition, a buffer may be added to the filling material to adjust the pH of the gel. One gel formulation of the present invention, in its preferred embodiment, consists of polyacrylamide and derivatives thereof. |
