| 摘要 |
<p>The present inventionprovides methods and compositions for orientation and covalent immobilization of protein on a surface, e,g., using light-mediated and/or oxidative reaction chemistry between functional groups on the surface and particular amino acid residue of the proteins. The present invention also provides protein arrays, such as protein arrays fabricated using light light mediated and oxidative chemistry. In particular, the invention provides methods for orientation and covalent immobilization of protein on a surface using light activated di-tyrosine cross-linking and arrays produced by light activated di-tyrosine cross-linking.</p> |
