发明名称 |
NOVEL PROTEINS AND DNAS THEREOF |
摘要 |
<p>The present invention provides proteins having the Na<+>/glucose transporter activity, DNAs encoding the proteins, a method of screening for a compound enhancing or inhibiting the activity of the proteins, and compounds obtained by the screening method. The proteins having the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, 15 or 26 arc useful as a diagnostic marker for a disease such as diabetes. The compounds enhancing or inhibiting the activity of the proteins, obtained the screening method using the proteins, can be used as a prophylactic and/or therapeutic agent for a disease such as diabetes and hyperlipidemia.</p> |
申请公布号 |
EP1357186(A1) |
申请公布日期 |
2003.10.29 |
申请号 |
EP20010995028 |
申请日期 |
2001.12.27 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
IWAMOTO, KEIJI;KATAYAMA, NOZOMI;KAWAMURA, MIHOKO |
分类号 |
A61K38/00;A61P3/06;A61P3/10;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N15/12;(IPC1-7):C12N15/12;C07K16/18;C12N5/10;A61K45/00;A61K48/00;G01N33/53;G01N33/50;G01N33/15;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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