发明名称 TNFa PRODUCTION INHIBITORS
摘要 There is provided a medicinal composition containing aminomethanesulfonic acid (including that in a form of salt or ester) as an active ingredient. Since it has an excellent effect of inhibiting the production of TNF alpha as compared with glycine which has been proposed already, the composition is expected as a drug for liver diseases. There are also provided a use of the above-mentioned active ingredient for drugs, a method for inhibiting the production of TNF alpha and, particularly, a method of treatment, amelioration and/or prevention of liver diseases utilizing the above method.
申请公布号 EP1356810(A1) 申请公布日期 2003.10.29
申请号 EP20010273986 申请日期 2001.12.18
申请人 AJINOMOTO CO., INC. 发明人 ISHIZAKI, S.;SONAKA, ICHIRO;IINO, YUKIO
分类号 A61K31/185;A61K31/255;A61P1/16;A61P43/00;(IPC1-7):A61K31/185 主分类号 A61K31/185
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