发明名称 |
METHOD OF TREATING COLONIC ADENOMAS |
摘要 |
This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising t he administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as define d herein.
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申请公布号 |
CA2227238(C) |
申请公布日期 |
2003.10.28 |
申请号 |
CA19962227238 |
申请日期 |
1996.07.15 |
申请人 |
MERCK FROSST CANADA & CO.;MERCK & CO., INC. |
发明人 |
SIMON, THOMAS J.;EVANS, JILLY;KARGMAN, STACIA |
分类号 |
A61K31/00;A61K31/12;A61K31/18;A61K31/19;A61K31/192;A61K31/195;A61K31/196;A61K31/34;A61K31/365;A61K31/405;A61K31/407;A61K31/54;A61K31/5415;(IPC1-7):A61K31/40;A61K31/275;A61K31/38 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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