发明名称 |
Library design in combinatorial chemistry by Monte Carlo methods |
摘要 |
Methods for generating multiple rounds of combinatorial libraries, which use Monte Carlo methods to search the multi-dimensional composition and non-composition space of variables in combinatorial chemistry; the combinatorial libraries generated and screened by such Monte Carlo methods; and an apparatus for generating and screening such libraries robotically. The process involves preparing a first set of samples, then changing the composition and non-composition variables of the samples using Monte Carlo sampling methods, and accepting proposed new samples according to a detailed balance acceptance criterion.
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申请公布号 |
US6640191(B1) |
申请公布日期 |
2003.10.28 |
申请号 |
US19990474965 |
申请日期 |
1999.12.30 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DEEM MICHAEL W.;FALCIONI MARCO |
分类号 |
C40B10/00;C40B20/00;C40B30/08;C40B40/18;C40B60/14;G01N31/10;(IPC1-7):G01N33/48;G01N31/00;G01N33/566;G01N33/543;G01N33/536;C12Q1/00;C12Q1/68 |
主分类号 |
C40B10/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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