发明名称 |
Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds |
摘要 |
An aromatic sulfonyl alpha-cycloamino hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated aromatic sulfonyl alpha-cycloamino hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
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申请公布号 |
US6638952(B1) |
申请公布日期 |
2003.10.28 |
申请号 |
US19990254530 |
申请日期 |
1999.12.23 |
申请人 |
PHARMACIA CORPORATION |
发明人 |
LI HUI;BECKER DANIEL P.;VILLAMIL CLARA I.;BOEHM TERRI L.;GETMAN DANIEL P.;MCDONALD JOSEPH J.;DECRESCENZO GARY A. |
分类号 |
C07C317/22;C07C317/44;C07C323/65;C07D207/16;C07D211/62;C07D213/30;C07D213/82;C07D295/15;(IPC1-7):A61K31/445;C07D211/22 |
主分类号 |
C07C317/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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