The invention provides methods and compositions for selectively acylating a specific hydroxyl group in a molecule of interest containing at least two unprotected secondary hydroxyl groups. Although the methods and compositions of the invention have general applicability, they are particularly useful in the selective acylation of the taxane molecules.
申请公布号
WO03087078(A1)
申请公布日期
2003.10.23
申请号
WO2003US10556
申请日期
2003.04.05
申请人
NATURAL PHARMACEUTICALS, INC.;JOHNSON, JAMES, H.;PARIZA, RICHARD, J.;GALLAGHER, REX, T.
发明人
JOHNSON, JAMES, H.;PARIZA, RICHARD, J.;GALLAGHER, REX, T.