发明名称 |
INHIBITORS OF AKT ACTIVITY |
摘要 |
The present invention is directed to compounds comprising a 2,3- diphenylpyrazine moiety which inhibit the activity of Akt, a serine/threonin e protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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申请公布号 |
CA2481229(A1) |
申请公布日期 |
2003.10.23 |
申请号 |
CA20032481229 |
申请日期 |
2003.04.04 |
申请人 |
MERCK & CO., INC. |
发明人 |
ZHAO, ZHIJIAN;LINDSLEY, CRAIG W.;DUGGAN, MARK E. |
分类号 |
A61K31/497;A61K45/00;A61P35/00;A61P43/00;C07D241/18;C07D401/14;(IPC1-7):C07D401/14;C07D241/10;C07D401/10;C07D403/10;A61K31/496 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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