NON-PRIMATE FXRb AS A LANOSTEROL SENSING NUCLEAR HORMONE RECEPTOR AND RELATED USES

摘要

The present invention relates to a novel nuclear receptor called 'npFXRB' or also npFXR-β a homologue of the npFXR-α, a prototypical type 2 nuclear receptor. The invention also relates to the isolated nucleic acid sequence of npFXRB and the isolated protein thereof. The inven­tion further relates to processes for isolating and/or producing the nucleic acid or the protein as well as methods of use of the receptor npFXRB.