| 摘要 |
<p>A compound is provided for increasing the concentration of a parent isoflavone in a subject in vivo. The parent isoflavone has a skeletal structure including a 5 position and a 7 position, a 5 alkyl group, and a 7-hydroxy_ grouo with a 7-hydroxy oxygen appended to the 7 position and a 7-hydroxy hydrogen appended to the 7-hydroxy oxygen. The compound includes a substrate having the skeletal structure of the parent isoflavone, with a 5 position and a 7 position corresponding to the 5 and 7 positions respectively of the parent isoflavone. An alkyl group is appended to the 5 position. A promoiety is appended to the 7-hydroxy oxygen of the substrate as a substitute fir the 7-hydroxy hydrogen of the parent isoflavone, the promoiety and the 7-hydroxy oxygen establishing an alkylcarbonate ester including an alkyl group having at least three carbon atoms. Wherein R1 consists of a member selected from the group consisting of a straight- chain, branched, and cyclic alkyl comprising at least three carbon atoms; R2 consists of a member selected from the group consisting of a straight-chain, branched, and cyclic alkyl; R?3 and R4¿ are the same or different, and selected from the group consisting of hydrogen, alkyl, hydroxy, and alkyoxy; and R5 consists of a member selected from the group consisting of hydrogen and an alkyl.</p> |
