| 摘要 |
<p>The present invention provides a novel metal chelate composition and its macromolecule complex. The invention also provides a preparation method of the metal chelate composition and method of using the metal chelate composition in purifying substance like peptide. The metal chelate composition of the present invention is expressed by the formula HS-R.sub.1 -CH(COOH)-N-(CH.sub.2 COOH).sub.2 (wherein R.sub.1 represents alkyl group linker having 1∼5 carbon atoms), and exhibits sufficient affinity and stability on the substance to be purified by simple process.</p> |
