| 摘要 |
This invention provides a compound of the formula (1) wherein: R1 represents a hydrogen atom, an alkyl group, etc.; R2 represents a hydrogen atom, a haloge n atom, etc.; R3 represents a hydrogen atom, an alkyl group, etc.; R4 represen ts an aryl group, etc.; A represents an aryl1, etc; B represents an alkylene etc.; X represents NH, etc.; or a phannaceutically acceptable ester of such compound, and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of medical conditions mediated by prostaglandins su ch as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
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