发明名称 PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS
摘要 This invention provides a compound of the formula (I): wherein: R1 represent s a hydrogen atom, an alkyl group, etc.; R2 represents a hydrogen atom, a halogen atom, etc.; R3 represents an alkyl group, etc.; R4 represents an ary l group, etc.; A represents an aryll, etc; B represents an alkylene etc.; X represents NH, etc.; or a pharmaceutically acceptable ester of such compound , and pharmaceutically acceptable salts thereof. These compounds are useful fo r the treatment of medical conditions mediated by prostaglandin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
申请公布号 CA2482382(A1) 申请公布日期 2003.10.23
申请号 CA20032482382 申请日期 2003.04.02
申请人 PFIZER INC. 发明人 YAMAGISHI, TATSUYA;NUKUI, SEIJI;NAKAO, KAZUNARI;HIRANO, MISATO
分类号 A61K31/415;A61K31/4155;A61K31/4178;A61K31/427;A61K31/4439;A61K31/506;A61P1/04;A61P7/04;A61P9/00;A61P11/06;A61P13/12;A61P15/00;A61P17/02;A61P19/00;A61P19/02;A61P19/06;A61P19/10;A61P25/04;A61P25/06;A61P25/28;A61P27/06;A61P27/14;A61P29/00;A61P35/00;A61P37/02;A61P37/08;C07D231/12;C07D231/16;C07D231/38;C07D401/04;C07D401/12;C07D403/12;C07D417/04;C07D417/12;C07D521/00;(IPC1-7):C07D231/12;C07D231/14;A61K31/41;A61K31/443;A61K31/470 主分类号 A61K31/415
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