| 发明名称 |
RECOMBINANT ANTI-INTERLEUKIN-9 ANTIBODIES |
| 摘要 |
<p>The application describes neutralizing chimeric and humanized anti-human IL- 9 antibodies, and the use thereof to identify neutralizing epitopes on human I L- 9 and as medicaments to prevent and treat asthma, bronchial hyperresponsiveness, atopic allergy, and other related disorders. Particular ly disclosed are recombinant antibodies derived from three murine anti-human IL -9 antibodies identified infra as MH9A3, MH9D1, and MH9L1.</p> |
| 申请公布号 |
CA2481747(A1) |
申请公布日期 |
2003.10.23 |
| 申请号 |
CA20032481747 |
申请日期 |
2003.04.11 |
| 申请人 |
MEDIMMUNE, INC.;LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
REED, JENNIFER LYNNE;VAN SNICK, JACQUES;DALL'ACQUA, WILLIAM;RENAULD, JEAN-CHRISTOPHE;CORMONT, FRANCOISE;UYTTENHOVE, CATHERINE |
| 分类号 |
C12N15/09;A61K39/395;A61P1/04;A61P1/16;A61P3/10;A61P5/00;A61P5/14;A61P7/00;A61P7/04;A61P7/06;A61P9/00;A61P9/14;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P15/08;A61P17/00;A61P17/04;A61P19/00;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K16/24;C07K19/00;C12P21/08;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
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