发明名称 |
USE OF NA,K-ATPASE A-AND B-SUBUNITS IN BLADDER CANCER DETECTION AND DRUG SCREENING |
摘要 |
Methods are provided for determining the malignancy of cells in a bladder carcinoma sample. Expression patterns of Na,K-ATPase .alpha. and .beta. subunits are shown to be associated with recurrence risk in these cancers. Detection of Na,K-ATPase .alpha. and .beta. subunits expression in bladder carcinomas provides a useful diagnostic for predicting patient prognosis and probability of drug effectiveness. Na,K-ATPase .alpha. and .beta. subunits provide a target for drug screening.
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申请公布号 |
CA2480665(A1) |
申请公布日期 |
2003.10.23 |
申请号 |
CA20032480665 |
申请日期 |
2003.04.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
RAJASEKARAN, AYYAPPAN K.;RAJASEKARAN, SIGRID A. |
分类号 |
C12Q1/34;G01N33/574;(IPC1-7):C12Q1/68;C12Q1/42;G01N33/573 |
主分类号 |
C12Q1/34 |
代理机构 |
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代理人 |
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地址 |
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