发明名称 |
INHIBITORS OF AKT ACTIVITY |
摘要 |
The present invention is directed to compounds comprising a 2,3-diphenylpyrazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. |
申请公布号 |
EP1494675(A2) |
申请公布日期 |
2003.10.23 |
申请号 |
EP20030746593 |
申请日期 |
2003.04.04 |
申请人 |
MERCK & CO., INC. |
发明人 |
DUGGAN, MARK, E.;LINDSLEY, CRAIG, W.;ZHAO, ZHIJIAN |
分类号 |
C07D401/14;A61K31/497;A61K45/00;A61P35/00;A61P43/00;C07D241/18;(IPC1-7):A61K31/497 |
主分类号 |
C07D401/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|