发明名称 |
INTRAPLEURAL SINGLE-CHAIN UROKINASE ALONE OR COMPLEXED TO ITS SOLUBLE RECEPTOR PROTECTS AGAINST PLEURAL ADHESIONS |
摘要 |
The present invention relates to methods of preventing or decreasing the severity of scarring in a subject comprising: obtaining a pharmaceutical composition comprising a single chain urokinase plasminogen activator molecule (scuPA) or a scuPA mimetic; and administering the pharmaceutical composition to a subject; wherein scarring in the subject is either prevented or decreased relative to an amount of scarring that would be expected if the pharmaceutical composition were not administered to the subject. The invention also relates to methods of screening for compounds that prevent or decrease the severity of scarring in a subject. |
申请公布号 |
WO03086278(A2) |
申请公布日期 |
2003.10.23 |
申请号 |
WO2003US10323 |
申请日期 |
2003.04.04 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;IDELL, STEVEN |
发明人 |
IDELL, STEVEN |
分类号 |
A61K38/49;G01N33/50 |
主分类号 |
A61K38/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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