发明名称 Compositions and methods for WT1 specific immunotherapy
摘要 Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
申请公布号 US2003198622(A1) 申请公布日期 2003.10.23
申请号 US20020195835 申请日期 2002.07.12
申请人 CORIXA CORPORATION 发明人 GAIGER ALEXANDER;SMITHGALL MOLLY D.;CARTER DARRICK;CHEEVER MARTIN A.;MCNEILL PATRICIA D.;SUTHERLAND R. ALEC;MOSSMAN SALLY P.;EVANS LAWRENCE S.;SWANSON RYAN M.
分类号 A61K38/00;A61K39/00;A61K48/00;C07K14/47;C12N5/08;(IPC1-7):A61K48/00 主分类号 A61K38/00
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