发明名称 |
Adenovirus-mediated therapy for uterine fibroids |
摘要 |
The present invention provides methods of treating and preventing uterine fibroids that is non-surgical, using a modified estrogen receptor gene delivered via an adenoviral vector. The modified estrogen receptor induced apoptosis in vitro and decreased tumor growth in vivo. The invention provides a major improvement above that of current available procedures for women having uterine fibroids, or in preventing fibroids in women at risk of having fibroids. The present invention further provides a safe means of treating fibroids and preserving fertility in young women, or maintaining pregnancy in pregnant women having fibroids.
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申请公布号 |
US2003199472(A1) |
申请公布日期 |
2003.10.23 |
申请号 |
US20030392274 |
申请日期 |
2003.03.19 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;NORTHWESTERN UNIVERSITY |
发明人 |
AL-HENDY AYMAN;LEE EUN JIG;JAMESON J. LARRY |
分类号 |
A61K38/00;A61K48/00;C12N15/861;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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