| 摘要 |
The present invention relates to phenolic acid derivatives of the formula I and compositions for the preventing and the treating blood lipid level-related diseases comprising the phenolic acid derivatives. The compounds have excellent effects of reducing blood lipid level, inhibiting cholesterol metabolism-related enzymes and preventing and treating blood lipid level-related diseases. wherein, R<1>, R<2>, R<3>, R<4 >and R<5 >are independently hydrogen, hydroxy or C1-C6 alkoxy; R<6 >is R<a >is hydrogen or acetyl; R<b >is COOR<d >or CH2OR<d>; R<c >is hydrogen, benzyl, hydroxybenzyl, imidazolemethyl, indolemethyl, linear or branched C1-C6 alkyl, or C1-C6 alkyl substittuted with hydroxy, thiol(SH), thiomethyl(SCH3), NHR<d>, CNHNH2, CONH2 or COOR<d>; and R<d >is hydrogen, methyl, ethyl or benzyl.
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