STEALTHY POLYMERIC BIODEGRADABLE NANOSPHERES AND USES THEREOF
摘要
Disclosed herein are stealthy polymeric biodegradable nanospheres each comprising: (i) a polyester-polyethylene multiblock copolymer; (ii) optionally a polyester entangled with the multiblock copolymer to give rigidity to the nanospheres; and (iii) optionally a pharmaceutical compound incorporated therein. Also disclosed is the use of such nanospheres for the preparation of a medicament having a long-term and non-toxic release of a pharmaceutical compound into a mammal, and the method for preparing a stealthy polymeric biodegradable nanospheres.
申请公布号
WO03086369(A2)
申请公布日期
2003.10.23
申请号
WO2003CA00499
申请日期
2003.04.04
申请人
UNIVERSITE DE MONTREAL;HILDGEN, PATRICE;PANOYAN, AVEDIS;LACASSE, FRANCOIS-XAVIER;QUESNEL, RICHARD;RIZKALLA, NEVINE