发明名称 Geometrically restricted 2-indolinone derivatives as modulators of protein kinase activity
摘要 The present invention relates to novel geometrically restricted 2-indolinones and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
申请公布号 US2003199510(A1) 申请公布日期 2003.10.23
申请号 US20030342194 申请日期 2003.01.15
申请人 SUGEN, INC. 发明人 TANG PENG CHO;MILLER TODD ANTHONY;SUN LI;TRAN NGOC MY;NEMATALLA ASAAD;NGUYEN ANH THI
分类号 A61K31/404;A61K31/34;A61K31/35;A61K31/36;A61K31/38;A61K31/385;A61K31/39;A61K31/40;A61K31/403;A61K31/405;A61K31/41;A61K31/415;A61K31/42;A61K31/425;A61K31/435;A61K31/44;A61K31/445;A61K31/495;A61K31/50;A61K31/505;A61K31/517;A61K31/519;A61K31/53;A61K31/535;A61K31/54;A61P3/10;A61P7/00;A61P9/08;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07D209/12;C07D209/34;C07D231/54;C07D235/02;C07D237/26;C07D239/70;C07D241/36;C07D249/16;C07D251/16;C07D251/72;C07D253/065;C07D253/08;C07D257/04;C07D257/08;C07D257/10;C07D261/08;C07D261/20;C07D263/32;C07D263/52;C07D265/12;C07D265/16;C07D265/34;C07D265/36;C07D271/04;C07D271/06;C07D271/08;C07D271/10;C07D271/12;C07D273/04;C07D275/02;C07D275/04;C07D279/06;C07D279/08;C07D279/12;C07D279/14;C07D279/16;C07D285/06;C07D285/08;C07D285/10;C07D285/12;C07D285/14;C07D285/18;C07D285/20;C07D285/22;C07D285/34;C07D291/02;C07D291/08;C07D307/36;C07D307/38;C07D307/40;C07D307/52;C07D307/77;C07D311/02;C07D311/94;C07D317/04;C07D317/06;C07D317/14;C07D317/44;C07D317/46;C07D319/06;C07D319/08;C07D319/12;C07D319/14;C07D319/16;C07D323/02;C07D323/04;C07D327/04;C07D327/06;C07D327/10;C07D333/06;C07D333/50;C07D401/02;C07D401/10;C07D403/04;C07D471/02;C07D487/02;(IPC1-7):C07D487/02 主分类号 A61K31/404
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