| 发明名称 |
N-SUBSTITUTED PYRIDINONE AND PYRIMIDINONE DERIVATIVES FOR USE AS LP-PLA2 INHIBITORS IN THE TREATMENT OF ARTHEROSCLEROSIS |
| 摘要 |
Compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. In Formula (I), R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, X and Y are as defined in the claims.
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| 申请公布号 |
WO03086400(A1) |
申请公布日期 |
2003.10.23 |
| 申请号 |
WO2003GB01544 |
申请日期 |
2003.04.10 |
| 申请人 |
GLAXO GROUP LIMITED;LEACH, COLIN, ANDREW;SMITH, STEPHEN, ALLAN |
发明人 |
LEACH, COLIN, ANDREW;SMITH, STEPHEN, ALLAN |
| 分类号 |
A61K31/4545;A61K31/4709;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P31/04;A61P43/00;C07D401/12;C07D401/14;C07D413/14;C07D417/14;C07D471/04;(IPC1-7):A61K31/470;A61K31/506 |
主分类号 |
A61K31/4545 |
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