发明名称 |
PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS |
摘要 |
This invention provides a compound of the formula (I): wherein: R<1> represents a hydrogen atom, an alkyl group, etc.; R<2> represents a hydrogen atom, a halogen atom, etc.; R<3> represents an alkyl group, etc.; R<4> represents an aryl group, etc.; A represents an aryl<l>, etc; B represents an alkylene etc.; X represents NH, etc.; or a pharmaceutically acceptable ester of such compound, and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of medical conditions mediated by prostaglandin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
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申请公布号 |
WO03087061(A1) |
申请公布日期 |
2003.10.23 |
申请号 |
WO2003IB01277 |
申请日期 |
2003.04.02 |
申请人 |
PFIZER PHARMACEUTICALS INC.;HIRANO, MISATO;NAKAO, KAZUNARI;NUKUI, SEIJI;YAMAGISHI, TATSUYA;PFIZER INC. |
发明人 |
HIRANO, MISATO;NAKAO, KAZUNARI;NUKUI, SEIJI;YAMAGISHI, TATSUYA |
分类号 |
A61K31/415;A61K31/4155;A61K31/4178;A61K31/427;A61K31/4439;A61K31/506;A61P1/04;A61P7/04;A61P9/00;A61P11/06;A61P13/12;A61P15/00;A61P17/02;A61P19/00;A61P19/02;A61P19/06;A61P19/10;A61P25/04;A61P25/06;A61P25/28;A61P27/06;A61P27/14;A61P29/00;A61P35/00;A61P37/02;A61P37/08;C07D231/12;C07D231/16;C07D231/38;C07D401/04;C07D401/12;C07D403/12;C07D417/04;C07D417/12;C07D521/00;(IPC1-7):C07D231/12;C07D231/14;A61K31/41;A61K31/443;A61K31/470 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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