发明名称 |
Induction of insulin-producing cells |
摘要 |
<p>What is described is a method for preparation of insulin-producing cells from non-insulin-producing cells. Mammalian fetal hepatocytes or hepatic progenitor cells are used ad the non- insulin-producing cells, and the method comprises culturing the mammalian fetal hepatocytes or the hepatic progenitor cells with 1-50 mmol/L of nicotinamide and concurrently bringing about expression of the PDX-1 gene or the NeuroD gene in the mammalian fetal hepatocytes.</p> |
申请公布号 |
EP1354942(A1) |
申请公布日期 |
2003.10.22 |
申请号 |
EP20030008738 |
申请日期 |
2003.04.16 |
申请人 |
JCR PHARMACEUTICALS CO., LTD.;SEINO, SUSUMU |
发明人 |
SEINO, SUSUMU;ISHIZUKA, NOBUKO;OKUNO, MASAAKI |
分类号 |
C12N5/071;C12N15/09;C12N5/10;(IPC1-7):C12N5/06 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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